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ISSN: 1553-619X (Print)
ISSN: 1558-3775 (Online)
Research Article Open Access

β-Glucan in Allergies

Sima Petr1 and Vetvicka Vaclav2
  • 1 Laboratory of Immunotherapy, Czech Republic
  • 2 University of Louisville, United States

Abstract

Multiple effects of β-glucan are well established. Together with the effects on antibacterial and anticancer immunity, glucan has been shown to stimulate bone marrow cells, lower cholesterol and to protects against stress and some kinds of poisoning. However, despite literally thousands of papers describing biological effects of β-glucan, only limited attention has been focused on the role of β-glucan in allergic reactions. Our review is focused on evaluating the current knowledge of the possible role of β-glucan in allergic reactions. Most of published studies concur that based on the improved Th1/Th2 balance, β-glucan showed a potential for development as an adjunct to the standard treatment of in patients with allergies.

American Journal of Immunology
Volume 13 No. 1, 2017, 73-80

DOI: https://doi.org/10.3844/ajisp.2017.73.80

Submitted On: 15 November 2016 Published On: 30 March 2017

How to Cite: Petr, S. & Vaclav, V. (2017). β-Glucan in Allergies. American Journal of Immunology, 13(1), 73-80. https://doi.org/10.3844/ajisp.2017.73.80

Open AccessCopyright: © 2017 Sima Petr and Vetvicka Vaclav. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Keywords

  • Glucan
  • Allergy
  • CR3
  • Cancer