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Advance in the Diagnostics of Mare Pregnancy and Assessing the Activity of Gonadotropin in Serum of in-Foal Mare

Kaliya Kudaikulovna Yerkekulova1, Nuradin Alibayev1, Yusupzhan Artykovich Yuldashbayev2, Oralbek Alikhanov1, Orynbek Beketauov1 and Dastanbek Asylbekovich Baimukanov3
  • 1 Agricultural Biotechnology Research Laboratory, M. Auezov South Kazakhstan University, Shymkent, Kazakhstan
  • 2 Department of Private Animal Science, Russian State Agrarian University-Moscow Timiryazev Agricultural Academy, Moscow, Russia
  • 3 Department of Animal Husbandry, Veterinary Medicine and Feed and Milk Quality Assessment, Scientific and Production Center for Animal Husbandry and Veterinary, Astana, Kazakhstan

Abstract

Research works on the improvement of mare pregnancy diagnostics and evaluation of biological activity of gonadotropic preparation based on the use of enzyme-linked immunosorbent assay were carried out. As the result of diagnostics and evaluation, effective producers as donors for obtaining gonadotropic preparation among the Kazakh population of mares with type “zhabe”, the animal units of 60 days with their 5-6 year pregnancy containing FSH -10,38±0,65 mIU/1 mL and 7-8-year-old with FSH content -10,50±0,32 mIU/1 mL; 70 days of their 3-4-year-old pregnancy with FSH content -10,52±0,21 mIU/1 mL, 5-6-year-old with FSH content -11,34±0,45 mIU/1mL, 7-8-year-old with FSH content -11,34±0,32 mIU/1 mL, 9-10-year-old with FSH content -11,06±0,29 mIU/1 mL are identified. A new method for the selection of a drug by biological activity based on the content of follicle-stimulating hormone level for a given herd was developed, which allows to determination of the activity in international units, without the traditional, labor-consuming, outdated method for determination using laboratory white mice, addressing ethical issues in research.

OnLine Journal of Biological Sciences
Volume 24 No. 3, 2024, 395-402

DOI: https://doi.org/10.3844/ojbsci.2024.395.402

Submitted On: 8 December 2023 Published On: 7 March 2024

How to Cite: Yerkekulova, K. K., Alibayev, N., Yuldashbayev, Y. A., Alikhanov, O., Beketauov, O. & Baimukanov, D. A. (2024). Advance in the Diagnostics of Mare Pregnancy and Assessing the Activity of Gonadotropin in Serum of in-Foal Mare. OnLine Journal of Biological Sciences, 24(3), 395-402. https://doi.org/10.3844/ojbsci.2024.395.402

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Keywords

  • Mare
  • Producer
  • Blood Sample
  • Mare Age
  • Gonadotropic Hormone Activity
  • Follicle-Stimulating Hormone
  • Luteinizing Hormone
  • Gonadotropic Hormone