Unveiling the Complex Relationship between Polycystic Ovary Syndrome and Cardiovascular Risk Factors: A Comprehensive Review
- 1 Institute for Atherosclerosis Research, Moscow, Russia
- 2 Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow, Russia
- 3 Petrovsky National Research Centre of Surgery, Moscow, Russia
- 4 Department of Polyclinic Therapy, NN Burdenko Voronezh State Medical University, 10 Studencheskaya Street, Voronezh, Russia
- 5 Institute on Aging Research, Russian Gerontology Clinical Research Centre, Pirogov Russian National Research Medical University, 16, 1st Leonova Street, Moscow, Russia
Abstract
Polycystic ovary syndrome remains a relatively unexplored endocrine disorder with significant implications for female health. Despite its prevalence and known associations with various metabolic disorders, the specific link between polycystic ovary syndrome and cardiovascular risk factors, particularly atherosclerosis, remains inadequately understood. This review aims to address the existing research gap by investigating the connection between polycystic ovary syndrome and cardiovascular risk factors. The objectives include examining the predisposition to atherosclerosis in females with polycystic ovary syndrome, assessing the impact of associated conditions like diabetes, dyslipidemia and obesity on cardiovascular health and highlighting the need for further investigation to clarify conflicting evidence in this area. This comprehensive review aims to provide insights into the complex interplay between polycystic ovary syndrome and cardiovascular and cardiometabolic risk factors, emphasizing the necessity for detailed studies to enhance understanding of this widespread condition.
DOI: https://doi.org/10.3844/ojbsci.2025.10.21
Copyright: © 2025 Anastasia Vladimirovna Poznyak, Victoria Alexandrovna Khotina, Vasily Nikolaevich Sukhorukov, Tatiana Ivanovna Kovyanova, Irina Alexandrovna Starodubtseva, Natalia V. Elizova, Alexey Viktorovich Churov and Alexander Nikolaevich Orekhov. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Keywords
- Atherosclerosis
- Cardiovascular Disease
- Ovaries
- PCOS